Comparing functional connectivity via thresholding correlations and SVD

نویسندگان

  • Keith J. Worsley
  • Jen-I Chen
  • Jason Lerch
  • Alan C. Evans
چکیده

Abstract We compare two common methods for detecting functional connectivity: thresholding correlations and Singular Value Decomposition (SVD). We find that thresholding correlations is better at detecting focal regions of correlated voxels, whereas SVD is better at detecting extensive regions of correlated voxels. We apply these results to resting state networks in an fMRI data set, and to look for connectivity in cortical thickness.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparing functional connectivity via thresholding correlations and singular value decomposition.

We compare two common methods for detecting functional connectivity: thresholding correlations and singular value decomposition (SVD). We find that thresholding correlations are better at detecting focal regions of correlated voxels, whereas SVD is better at detecting extensive regions of correlated voxels. We apply these results to resting state networks in an fMRI dataset to look for connecti...

متن کامل

Probabilistic thresholding of functional connectomes: Application to schizophrenia

Functional connectomes are commonly analysed as sparse graphs, constructed by thresholding cross-correlations between regional neurophysiological signals. Thresholding generally retains the strongest edges (correlations), either by retaining edges surpassing a given absolute weight, or by constraining the edge density. The latter (more widely used) method risks inclusion of false positive edges...

متن کامل

Identification of mild cognitive impairment disease using brain functional connectivity and graph analysis in fMRI data

Background: Early diagnosis of patients in the early stages of Alzheimer's, known as mild cognitive impairment, is of great importance in the treatment of this disease. If a patient can be diagnosed at this stage, it is possible to treat or delay Alzheimer's disease. Resting-state functional magnetic resonance imaging (fMRI) is very common in the process of diagnosing Alzheimer's disease. In th...

متن کامل

Proportional thresholding in resting-state fMRI functional connectivity networks and consequences for patient-control connectome studies: Issues and recommendations

Graph theoretical analysis has become an important tool in the examination of brain dysconnectivity in neurological and psychiatric brain disorders. A common analysis step in the construction of the functional graph or network involves "thresholding" of the connectivity matrix, selecting the set of edges that together form the graph on which network organization is evaluated. To avoid systemati...

متن کامل

Brain Functional Connectivity Changes During Learning of Time Discrimination

The human brain is a complex system consist of connected nerve cells that adapts with and learn from the environment by changing its regional activities. Synchrony between these regional activities called functional network changes during the life, and with learning of new skills. Time perception and interval discrimination are among the most necessary skills for the human being to perceive mot...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2005